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5 Htp - 5 Hydroxytryptophan (5-HTP) and tryptophan are so-called natural alternatives to traditional antidepressants, used to treat unipolar depression and dysthymia. 5-HTP is an amino acid that is the intermediate step between tryptophan and the important brain chemical serotonin basically 5-HTP is a forerunner to the neurotransmitter serotonin, which transfers nerve impulses from one cell to another and regulates several vital processes in the body. Buy 5 Htp Supplements at HerbsMD.